The Human Phenotype Ontology (HPO) provides the following list of features that have been reported in people with this condition. Much of the information in the HPO comes from Orphanet, a European rare disease database. If available, the list includes a rough estimate of how common a feature is (its frequency). Frequencies are based on a specific study and may not be representative of all studies. You can use the MedlinePlus Medical Dictionary for definitions of the terms below.
|Signs and Symptoms||Approximate number of patients (when available)|
|Abnormality of the vertebrae||90%|
|Abnormality of the urinary system||7.5%|
|Aplasia/Hypoplasia of the corpus callosum||7.5%|
|Tetralogy of Fallot||7.5%|
|Agenesis of cerebellar vermis||-|
|Cranial nerve paralysis||-|
|Dilated fourth ventricle||-|
|Elevated imprint of the transverse sinuses||-|
|Partial absence of cerebellar vermis||-|
|Posterior fossa cyst at the fourth ventricle||-|
|Thinning and bulging of the posterior fossa bones||-|
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Nonprofit support and advocacy groups bring together patients, families, medical professionals, and researchers. These groups often raise awareness, provide support, and develop patient-centered information. Many are the driving force behind research for better treatments and possible cures. They can direct people to research, resources, and services. Many groups also have experts who serve as medical advisors. Visit their website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
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My wife is 17 weeks pregnant. During a level 2 ultrasound scan, the doctor told us there is a problem with the development of the cerebellar vermis. Can the vermis develop after 17 weeks? If a child is born with this, what problems could the child face? What are other tests we can do to confirm the condition? See answer
Can a child have Dandy-Walker variant and have other extracranial malformations, such as kidney and foot issues? Or does the presence of other issues point toward the more serious Dandy-Walker malformation? See answer
My husband was diagnosed with Dandy Walker variant at the age of 50. His brain surgeon placed a shunt. We have three children of adult age. Should they be concerned that this can be passed on? He went his whole life not knowing he had Dandy Walker till problems neurologically started happening and was in critical condition. How long can a person live with this once shunted and can our children be concerned that this is passed on? See answer
What is the life expectancy of someone with Dandy-Walker complex? See answer