According to the original classification, there are three types of dentinogenesis imperfecta:
Type I: occurs in people who have osteogenesis imperfecta, a genetic condition in which bones are brittle, causing them to break easily. People with this type of dentinogenesis imperfecta have mutations in COL1A1 or COL1A2.
Type II: usually occurs in people without another inherited
disorder. Some families with type II also have progressive
Type III: usually occurs in people without another inherited disorder. Type III was first identified in a group of families in southern Maryland and has also been seen in individuals of Ashkenazi Jewish descent.
Some researchers believe that dentinogenesis imperfecta type II and type III, along with a similar condition called dentin dysplasia type II, are actually just different forms of a single disorder.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Assessing the Impact of Osteogenesis Imperfecta on Non-Skeletal Systems
Wednesday, April 18, 2012 -
Friday, April 20, 2012
Location: Sheraton Gateway Suites, Rosemont, IL
Description: This meeting will focus on the impact of abnormal collagen on health in an effort to broaden professional awareness of the full spectrum of issues faced by persons with OI as they age. The goals are: 1)-to review current knowledge regarding the impact of OI on a wide range of bodily systems during the aging process, 2)-identify major information gaps, 3)-make recommendations to expand the OI research agenda. A Workshop Report will be compiled following the meeting in order to share these findings with health professionals and the OI community.
Contact: Theresa Smith, NIAMS(301) email@example.com
Co-funding Institute(s): National Institute of Arthritis and Musculoskeletal and Skin Diseases, Office of Rare Diseases Research
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My 13-year-old son was diagnosed with dentinogenesis imperfecta when he was a baby. Are there any programs in New York to help with the cost of his dental work? See answer
I would like to learn more about dentinogenesis imperfecta. How is this condition treated? How can I get in touch with others affected by this condition? See answer