If both parents are heterozygotes (carry one factor V Leiden mutation) than they would have a 25% chance of having a child with two factor V Leiden mutations, a 25% chance of having a child with no mutations, and a 50% chance of having a child with one mutation.
Factor V Leiden increases the risk of developing a DVT during pregnancy by about seven-fold. Women with factor V Leiden who are planning pregnancy should discuss this with their obstetrician and/or hematologist. Most women with factor V Leiden have normal pregnancies and only require close follow-up during pregnancy. For those with a history of DVT or PE, treatment with an anticoagulant during a subsequent pregnancy can prevent recurrent problems. 
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I was diagnosed with factor V Leiden before I got pregnant. I am currently 38 weeks pregnant, and have never had a miscarriage nor have I had any VTE events. Even though I am only heterozygous and never had a clotting event before, it is apparently recommended that I be induced at 39 weeks. Who recommends this? Is the risk that high for a person to have to be induced at 39 weeks for a person who has never had a thrombotic event before? See answer
My sister has factor V Leiden, but I do not. Does this mean we are half sisters? There is some question regarding my sister's parentage. See answer
How does factor V Leiden affect a diabetic person (type 1)? What is the link between elevated Activated Protein C and Factor V Leiden? Are there symptoms that would indicate if a person has a clot? Are there any treatments? See answer
I have been diagnosed with Factor 5 Leiden. Is it unusual that I bruise easily? I would have expected the opposite. I have been tested twice so I know the diagnosis must be correct. See answer
Factor V Leiden runs in my family. My sister is now battling acute promyelocytic leukemia. Are these two conditions issues linked? Can Factor V Leiden bring on leukemia? Are they related in any way, shape, or form? See answer
I just found out I also have a MTHFR homozygous A1298C mutation. (the C677T mutation was NOT detected.) What does the combination of these two mutations mean for treatment and further testing recommendations? See answer
Wondering if there is a connection between factor V Leiden and breast cancer? I have read that many people with breast cancer have factor V Leiden, but wondering which came first? I have asked many people and no one seems to have the answer. See answer
I am heterozygous for a factor V Leiden mutation. I was on oral contraceptives for 10 years before trying to get pregnant. After two miscarriages, I was tested and I found out that I had this condition. I saw where you discuss oral contraceptives; but I didn't know if an IUD such as Mirena may be safer to use than an oral contraceptives? See answer
I have factor V Leiden and was wondering if it's safe to use oral contraceptives. I want to take the pill called Levlin. See answer
What is the name of the test that would be used to diagnose this condition? Is there more than one test? Most importantly, how accurate is this test for both positive and negative results? See answer
I was recently diagnosed with factor V Leiden. It was found when I needed surgery on my right ankle, which just broke without injury. I was on Coumadin, a blood thinner. Then two months after surgery, my left ankle broke in the same exact spot again just from being on crutches. The same bone broke at the exact spot on both ankles, so I started asking questions. My orthopedic surgeon said because of the factor V Leiden I was getting blood clots in the capillaries going to that section of my bone. The effect was of course bone death and breakage. I would like to know if my doctor's claims could be plausible. See answer
My grandmother on my dad's side has two copies of the factor V Leiden gene mutation. I have one copy. Do I need to go and see a hematologist to get on blood thinners, or is there really nothing that they would do since I only have the one copy? Also, if I have one copy does that mean that my father has two copies of it or could he possibly have only the one copy as well? See answer
My husband has factor V Leiden. How could he have this when nobody else in his family has it including his parents? Is this disorder always passed down or can it skip a generation? What is the chance that our kids will have it? See answer