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So far studies investigating the use of bisphosphonate therapies for treatment of fibrous dysplasia have been small and uncontrolled. Further information regarding the benefits and complications associated with bisphosphonate therapy for treatment of fibrous dysplasia is likely on the horizon. The National Institute of Dental and Craniofacial Research at the National Institutes of Health completed a three year, phase 2,
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In addition, there is an ongoing clinical trial in Europe, entitled Effect of Risedronate on Bone Morbidity in Fibrous Dysplasia of Bone (PROFIDYS), that is investigating the efficacy of oral bisphosphonate to decrease bone pain and improve radiological appearance of fibrous dysplasia. Click on the title above to learn more.