This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
|Medical Terms||Other Names||
|30%-79% of people have these symptoms|
|Abnormality of movement||
Unusual movement[ more ]
|Abnormality of the voice||
Psychiatric disturbances[ more ]
|Cerebral cortical atrophy||0002120|
Progressive dementia[ more ]
Loss of developmental milestones
Mental deterioration in childhood[ more ]
|5%-29% of people have these symptoms|
|Percent of people who have these symptoms is not available through HPO|
|Abnormality of eye movement||
Abnormal eye movement
Abnormal eye movements
Eye movement abnormalities
Eye movement issue[ more ]
Slowness of movements[ more ]
Degeneration of cerebellum
|Neuronal loss in
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Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Got a Great Research Idea? ‘All of Us’ Wants to Hear It!
January 18, 2018
New NCATS Rare Diseases Research Video
December 27, 2017
Rare Disease Day at NIH on March 1, 2018
December 19, 2017
Huntington Disease and the Potential of Gene Silencing
October 26, 2015
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question
My father has Huntington chorea and his body is stiffening up. I would like to know if this means he is going to pass away soon. His side of the family has had this disease. It has not skipped anyone yet. I was young and don't remember what happens. See answer
Resent test results showed 17 repeats from each parent. The social worker suggested that the test might be in error because the number of repeats is the same. Instead of telling the person they did not have HD, she suggested the test was in error. How likely or unlikely is it for the number of repeats to be the same? When one needs a definitive positive or negative, this negative result, being suggested as possibly an error, is heart wrenching, especially for the patient and her family. Is it uncommon for the numbers to be the same? Should she be retested? How common are mistakes in diagnosing HD? The patient lost a parent to HD. See answer
Can a person of any gender, age, or ethnicity have Huntington disease? See answer
I am a personal trainer working with a client who has HD. While I have seen progress with the exercises we are doing, I am looking for more information regarding the types of exercises that are found to be most effective or certain exercises that should be avoided. See answer
What tests will my doctor order to confirm if I have Huntington disease? See answer
A friend of mine has been diagnosed with Huntington disease. No one else in his family has this condition. Is it possible that a chemical exposure could have caused it, such as to vinyl chloride? See answer
I have a family history of Huntington's disease. My mother was diagnosed with it about 5 years ago. I just needed to know some information about where I can get tested. Also, how early can they start treatment if I am diagnosed with it? I'm only 21 years old. I just thought that maybe the sooner they start the better. See answer