Mal de debarquement

Title

Other Names:

MdDS; Mal de debarquement syndrome; Sickness of disembarkment; MdDS; Mal de debarquement syndrome; Sickness of disembarkment; Disembarkment syndrome See More

Categories:

Ear, Nose, and Throat Diseases; Nervous System Diseases

Summary Summary

Mal de debarquement syndrome is a balance disorder that most commonly develops following an ocean cruise or other type of water travel and less commonly following air travel, train travel, or other motion experiences. The symptoms typically reported include: persistent sensation of motion such as rocking, swaying, and/or bobbing, difficulty maintaining balance, anxiety, fatigue, unsteadiness, and difficulty concentrating. The symptoms may be last anywhere from a month to years. Symptoms may or may not go away with time; however, they may reoccur following another motion experience or during periods of stress or illness.^[1] Although there is no known cure for mal de debarquement syndrome, there is evidence that some patients have responded positively to antidepressants or anti-seizure medications. Customized vestibular therapy and exercise routines may also be effective.^[2]

Last updated: 5/20/2015

Treatment Treatment

Treatment options for mal de debarquement syndrome (MdDS) are limited.^[3]^[4]^[5]^[6] Most drugs that work for other forms of dizziness do not work for MdDS. On some cases, medications classified as vestibular suppressants, such as anti-depressants and anti-seizure medications, may be used.^[2] Customized vestibular therapy like optokinetic stimulation has been effective in some cases.^[2]^[4] In recent years, a renewed interest in understanding the underlying cause of MdDS has led to new treatment options, including repetitive cranial stimulation.^[5] More studies into these treatment options are needed.

Last updated: 11/26/2015

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Research Research

Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.

Clinical Research Resources

ClinicalTrials.gov lists trials that are studying or have studied Mal de debarquement. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.

Please note: Studies listed on the ClinicalTrials.gov website are listed for informational purposes only; being listed does not reflect an endorsement by GARD or the NIH. We strongly recommend that you talk with a trusted healthcare provider before choosing to participate in any clinical study.

Organizations Organizations

Nonprofit support and advocacy groups bring together patients, families, medical professionals, and researchers. These groups often raise awareness, provide support, and develop patient-centered information. Many are the driving force behind research for better treatments and possible cures. They can direct people to research, resources, and services. Many groups also have experts who serve as medical advisors. Visit their website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.

Organizations Supporting this Disease

MdDS Balance Disorder Foundation
22406 Shannondell Drive
Audubon, PA 19403
E-mail: mddsfoundation@yahoo.com
Website: http://www.mddsfoundation.org
Vestibular Disorders Association
5018 NE 15th Ave
Portland, OR 97211
Toll-free: 800-837-8428
Telephone: 503-229-7705
Fax: 503-229-8064
E-mail: info@vestibular.org
Website: http://www.vestibular.org

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Learn More Learn More

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

Where to Start

MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
The National Institute on Deafness and Other Communication Disorders (NIDCD) conducts and supports biomedical and behavioral research and research training in the normal and disordered processes of hearing, balance, smell, taste, voice, speech, and language. Click on the link to view information on this topic.
The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.

In-Depth Information

The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
PubMed is a searchable database of medical literature and lists journal articles that discuss Mal de debarquement. Click on the link to view a sample search on this topic.

Selected Full-Text Journal Articles

Cha YH, Cui Y, Baloh RW. Repetitive transcranial magnetic stimulation for Mal de Debarquement Syndrome Otol Neurotol. 2013 Jan; 34(1):175-179.
Dai M, Cohen B, Smouha E, Cho C. Readaptation of the Vestibulo-Ocular Reflex Relieves the Mal de Debarquement Syndrome Front Neurol. 2014 Jul 15; 5:124.

GARD Answers GARD Answers

Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question

Could you provide some information about optokinetic stimulation and cranial stimulation as treatments for mal de debarquement syndrome? See answer
Can you tell me if there is any information on prevention of symptoms of Mal de Debarquement? I had symptoms after a cruise and now experience symptoms after flying. I will be going on a cruise and flying to get there and want to see if there is anything I can do as a preventative. See answer

Have a question? Contact a GARD Information Specialist.

References References

About Mal de Debarquement Syndrome. MdDS Balance Disorder Foundation. http://www.mddsfoundation.org/about-mdds/. Accessed 5/20/2015.
Hain TC. Mal de Debarquement. National Organization for Rare Disorders (NORD). 2012; http://rarediseases.org/rare-diseases/mal-de-debarquement/.
Cha YH. Mal de debarquement syndrome: new insights. Ann N Y Acad Sci. 2015 Apr; 1343:63-8. http://www.ncbi.nlm.nih.gov/pubmed/25726862. Accessed 11/26/2015.
Dai M, Cohen B, Smouha E, Cho C. Readaptation of the Vestibulo-Ocular Reflex Relieves the Mal De Debarquement Syndrome. Front Neurol. 2014 Jul 15; 5:124. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097942/. Accessed 11/26/2015.
Cha YH, Cui Y, Baloh RW. Repetitive transcranial magnetic stimulation for Mal de Debarquement Syndrome. Otol Neurotol. 2013 Jan; 34(1):175-179. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529198/. Accessed 11/26/2015.
Shou G, Yuan H, Urbano D, Cha YH, Ding L. Changes of symptom and EEG in mal de debarquement syndrome patients after repetitive transcranial magnetic stimulation over bilateral prefrontal cortex: a pilot study. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:4294-7. http://www.ncbi.nlm.nih.gov/pubmed/25570942. Accessed 11/26/2015.