This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
|Medical Terms||Other Names||
|80%-99% of people have these symptoms|
Autoimmune disorder[ more ]
Tiredness[ more ]
Acid reflux disease
Heartburn[ more ]
Muscle pain[ more ]
|30%-79% of people have these symptoms|
Inflammation of tissues lining lungs and chest
Dry mouth syndrome
Reduced salivation[ more ]
|5%-29% of people have these symptoms|
Death of bone due to decreased blood supply
|Interstitial pulmonary abnormality||
Abnormality in area between air sacs in lung
Stiff joints[ more ]
Decreased blood leukocyte number
Low white blood cell count[ more ]
Swollen lymph nodes in center of chest
Inflammation of heart muscle
Breakdown of bone
Swelling or irritation of membrane around heart
|Prolonged bleeding time||0003010|
Increased blood pressure in blood vessels of lungs
Red or purple spots on the skin
Increased spleen size
Related diseases are conditions that have similar signs and symptoms. A health care provider may consider these conditions in the table below when making a diagnosis. Please note that the table may not include all the possible conditions related to this disease.
Conditions with similar signs and symptoms from Orphanet
Differential diagnoses include other connective tissue diseases such as SLE, SSc, PM and/or RA, and other systemic diseases such as sarcoidosis, periarteritis nodosa, or Still's disease (see these terms).
Visit the Orphanet disease page for more information.
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
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What can my son expect with this disease? He is 27 years old. Is this going to be disabling? See answer
What is the treatment or remedy of mixed connective tissue disorder? See answer
What causes mixed connective tissue disease? Is it genetic? Is it due to environmental exposures? See answer