This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
|Medical Terms||Other Names||
|30%-79% of people have these symptoms|
|Abnormality of the thymus||0000777|
|Acetylcholine receptor antibody positivity||0030208|
Difficulty articulating speech
|Muscle specific kinase antibody positivity||0030210|
Drooping upper eyelid
|Single fiber EMG abnormality||0030006|
|5%-29% of people have these symptoms|
Pins and needles feeling
|Primary adrenal insufficiency||0008207|
|Systemic lupus erythematosus||0002725|
|1%-4% of people have these symptoms|
|Percent of people who have these symptoms is not available through HPO|
|Limb muscle weakness||
|Proximal muscle weakness||0003701|
Normally when impulses travel down a nerve, the nerve endings release a neurotransmitter substance called acetylcholine. Acetylcholine travels from the neuromuscular junction - the place where nerve cells connect with the muscles they control - and binds to acetylcholine receptors which are activated and generate a muscle contraction. In myasthenia gravis, antibodies block, alter, or destroy the receptors for acetylcholine at the neuromuscular junction, which prevents a muscle contraction from occurring. These antibodies are produced by the body's own immune system.In some cases, MG is linked to
The resources below provide information about treatment options for this condition. If you have questions about which treatment is right for you, talk to your healthcare professional.
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Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question
My husband recently had a heart attack, and he also has myasthenia gravis (MG). He has no family or personal history of coronary problems, he is in great physical condition. Could the MG have contributed or be a cause of his heart attack? See answer
My brother has been diagnosed with myasthenia gravis and I am wondering how rare this illness is. Have statistics been figured out? See answer
What does myasthenia gravis do to my body? See answer
Is myasthenia gravis genetic? See answer