is a rare disease of unknown cause, characterized by overgrowth of mature, non-cancerous fat cells in the pelvic region. The symptoms of pelvic lipomatosis are related to the compression of the urinary system (urinary frequency
, and hematuria
), lower intestinal tract (constipation, tenesmus
, rectal bleeding, and ribbon-like stools with mucus), and vascular system (edema of lower extremities
). Pelvic lipomatosis has been linked to chronic lower urinary tract infections
, obesity, and endocrine dysfunction. Treatment usually seeks to alleviate symptoms, especially kidney obstruction and end stage renal disease. While most cases are not progressive, upper-tract urinary surgery may be needed for those with severe symptoms and/or evidence of urinary obstruction with deterioration of the kidney function.
Last updated: 6/10/2011