The Human Phenotype Ontology (HPO) provides the following list of features that have been reported in people with this condition. Much of the information in the HPO comes from Orphanet, a European rare disease database. If available, the list includes a rough estimate of how common a feature is (its frequency). Frequencies are based on a specific study and may not be representative of all studies. You can use the MedlinePlus Medical Dictionary for definitions of the terms below.
| Signs and Symptoms | Approximate number of patients (when available) |
| Arrhythmia | 90% |
| Cardiomyopathy | - |
| Palpitations | - |
| Paroxysmal atrial fibrillation | - |
| Paroxysmal supraventricular tachycardia | - |
| Prolonged QRS complex | - |
| Shortened PR interval | - |
| Stroke | - |
| Sudden cardiac death | - |
| Ventricular preexcitation with multiple accessory pathways | - |
| Wolff-Parkinson-White syndrome | - |
Most cases of Wolff-Parkinson-White syndrome occur in people with no apparent family history of the condition. These cases are described as sporadic and are not inherited.[1]
Familial Wolff-Parkinson-White syndrome accounts for only a small percentage of all cases of this condition. The familial form of the disorder typically has an autosomal dominant pattern of inheritance, which means one copy of the altered gene in each cell is sufficient to cause the condition. In most cases, a person with familial Wolff Parkinson White syndrome has inherited the condition from an affected parent.[1]
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Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
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Can you do weight training or any other types of exercises if you have Wolff-Parkinson-White syndrome? See answer
What percentage of patients with Wolff Parkinson White syndrome have Ebstein's anomaly? See answer
My son has been diagnosed with Wolff Parkinson White syndrome. Should other members of my family be tested for this condition? See answer
