The Human Phenotype Ontology (HPO) provides the following list of features that have been reported in people with this condition. Much of the information in the HPO comes from Orphanet, a European rare disease database. If available, the list includes a rough estimate of how common a feature is (its frequency). Frequencies are based on a specific study and may not be representative of all studies. You can use the MedlinePlus Medical Dictionary for definitions of the terms below.
| Signs and Symptoms | Approximate number of patients (when available) |
| Abnormality of neutrophils | 90% |
| Arthralgia | 90% |
| Arthritis | 90% |
| Autoimmunity | 90% |
| Limitation of joint mobility | 90% |
| Osteolysis | 90% |
| Abnormality of lymphocytes | 50% |
| Anemia | 50% |
| Lymphadenopathy | 50% |
| Otitis media | 50% |
| Recurrent pharyngitis | 50% |
| Sinusitis | 50% |
| Splenomegaly | 50% |
| Weight loss | 50% |
| Abnormality of the pericardium | 7.5% |
| Abnormality of the pleura | 7.5% |
| Bone marrow hypocellularity | 7.5% |
| Cellulitis | 7.5% |
| Generalized hyperpigmentation | 7.5% |
| Hepatomegaly | 7.5% |
| Inflammatory abnormality of the eye | 7.5% |
| Irregular hyperpigmentation | 7.5% |
| Lymphoma | 7.5% |
| Peripheral neuropathy | 7.5% |
| Pulmonary fibrosis | 7.5% |
| Recurrent urinary tract infections | 7.5% |
| Sepsis | 7.5% |
| Skin ulcer | 7.5% |
| Thrombocytopenia | 7.5% |
| Autosomal dominant inheritance | - |
| Neutropenia | - |
| Rheumatoid arthritis | - |
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Nonprofit support and advocacy groups bring together patients, families, medical professionals, and researchers. These groups often raise awareness, provide support, and develop patient-centered information. Many are the driving force behind research for better treatments and possible cures. They can direct people to research, resources, and services. Many groups also have experts who serve as medical advisors. Visit their website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question
My husband was diagnosed with Felty's syndrome and died a few months later. Is Felty's syndrome inherited? I am concerned that my son is at risk for having the condition. See answer
