The Human Phenotype Ontology (HPO) provides the following list of features that have been reported in people with this condition. Much of the information in the HPO comes from Orphanet, a European rare disease database. If available, the list includes a rough estimate of how common a feature is (its frequency). Frequencies are based on a specific study and may not be representative of all studies. You can use the MedlinePlus Medical Dictionary for definitions of the terms below.
|Signs and Symptoms||Approximate number of patients (when available)|
|Autosomal dominant inheritance||-|
|Autosomal recessive inheritance||-|
|Chronic kidney disease||-|
|Decreased serum complement factor H||-|
|Depletion of components of the alternative complement pathway||-|
|Glomerular subendothelial electron-dense deposits||-|
|Recurrent bacterial infections||-|
|Thickening of the glomerular basement membrane||-|
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My stepson had this disease and required a kidney transplant at age 13. He is now 25 and has a daughter. How possible is it that she might have this? What do we need to watch for? He had no family history of kidney disease. See answer
I am trying to find out more information about how to treat my condition. See answer
I have dense deposit disease. Are nausea and vomiting symptoms of the disease? See answer