Disease at a Glance

Summary
Glomus vagale tumor is a type of paraganglioma, which is a tumor that develops in the paraganglia (a group of cells that are found near nerve cell bunches called ganglia). Glomus vagale tumors, specifically, grow in the paraganglia located near the vagus nerve, an important cranial nerve which serves many functions including empowering the vocal cords and the muscles of swallowing. In most cases, the tumors are benign, although rare cancerous cases have been reported. Symptoms vary based on the size and location of the tumor but may include a neck mass, tinnitus (ringing or buzzing in the ears), difficulty swallowing, hoarseness, pain, cough, and/or cranial nerve paralysis. Some tumors may not be associated with any concerning features and are diagnosed by chance during imaging studies performed to investigate other conditions. In many cases, the underlying cause of Glomus vagale tumors is poorly understood, although it does affect multiple familiy members. Glomus vagale tumors can be associated with inherited syndromes caused by genetic changes in succinate dehydrogenase subunits (i.e. SDHB, SDHD, SDHA, SDHAF2, SDHC) or the MAX gene.
Estimated Number of People with this Disease

This section is currently in development.

What Information Does GARD Have For This Disease?

Many rare diseases have limited information. Currently GARD is able to provide the following information for this disease:

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Categories
When do symptoms of this disease begin?
This section is currently in development. 

Symptoms

This section is currently in development. We recommend speaking with a doctor to learn more about this disease. 

Causes

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Last Updated: Nov. 8, 2021