The Human Phenotype Ontology (HPO) provides the following list of features that have been reported in people with this condition. Much of the information in the HPO comes from Orphanet, a European rare disease database. If available, the list includes a rough estimate of how common a feature is (its frequency). Frequencies are based on a specific study and may not be representative of all studies. You can use the MedlinePlus Medical Dictionary for definitions of the terms below.
|Signs and Symptoms||Approximate number of patients (when available)|
|Abnormal form of the vertebral bodies||90%|
|Abnormality of the oral cavity||90%|
|Abnormality of the sacroiliac joint||90%|
|Inflammatory abnormality of the eye||90%|
|Abnormality of the thorax||50%|
|Abnormal tendon morphology||7.5%|
|Abnormality of temperature regulation||7.5%|
|Abnormality of the aortic valve||7.5%|
|Abnormality of the pericardium||7.5%|
|Abnormality of the pleura||7.5%|
|Recurrent urinary tract infections||7.5%|
|Inflammation of the large intestine||-|
Making a diagnosis for a genetic or rare disease can often be challenging. Healthcare professionals typically look at a person’s medical history, symptoms, physical exam, and laboratory test results in order to make a diagnosis. The following resources provide information relating to diagnosis and testing for this condition. If you have questions about getting a diagnosis, you should contact a healthcare professional.
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Nonprofit support and advocacy groups bring together patients, families, medical professionals, and researchers. These groups often raise awareness, provide support, and develop patient-centered information. Many are the driving force behind research for better treatments and possible cures. They can direct people to research, resources, and services. Many groups also have experts who serve as medical advisors. Visit their website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question
I am 25 years old. I was diagnosed with ankylosing spondylitis (grade 2) one and a half years ago. I am on NSAIDs presently. I have lower back pain and morning stiffness for 30 to 45 minutes. I do regular exercises. What can I do for normal spinal mobility and a healthy life? Is there any role of food in this disease? Will all patients with this disease become disabled and spines become fused? What are the chances of transmission of this disease to my offspring? What types of tests should I have each year? See answer
Can it affect the hands as well as other parts of the body? Also, can diet improve or vitamins help? The strong meds seem to make it worse - hard on the stomach and causing other medical problems. See answer
Is there an association between ankylosing spondylitis and Crohn's disease? See answer