I have a 7-year-old patient diagnosed with PLEVA by skin biopsy. He has a chronic and relapsing course and we are trying to find more information for the family regarding this condition, its outcomes, and long-term complications.
What are the signs and symptoms of pityriasis lichenoides et varioliformis acuta?
Pityriasis lichenoides et varioliformis acuta (PLEVA) is the acute form of a skin condition called pityriasis lichenoides. It is characterized by the sudden onset of red patches that quickly develop into scaling papules. These papules may become filled with blood and/or pus or erode into crusted red-brown spots. People may also experience burning and itching of the affected area. Scarring and/or temporary discoloration of the skin may be present after the lesions have healed.
Although PLEVA can affect almost any part of the body, it most commonly develops on the trunk and/or limbs (arms/legs). Affected people may have a few to more than one hundred papules. The skin abnormalities generally resolve without treatment in a few weeks to a few months; however, some people experience episodes of the condition on and off for years.
Aside from the skin findings, most affected people do not experience any additional signs and symptoms. However, some may experience fever, headaches, joint pain and swelling of nearby lymph nodes.
Febrile Ulceronecrotic Mucha-Haberman Disease is a rare and severe variant of PLEVA that is associated with unique signs and symptoms. For more information on this condition, please click here.
Last updated: 2/2/2015
How often does pityriasis lichenoides et varioliformis acuta turn into something more serious?
Pityriasis lichenoides et varioliformis acuta (PLEVA) may evolve into cutaneous lymphoma in less than 2% of cases.
What is the long-term outlook for people with pityriasis lichenoides et varioliformis acuta?
The long-term outlook (prognosis) for people with pityriasis lichenoides et varioliformis acuta (PLEVA) varies but is generally good. Most cases tend to resolve on their own in several weeks to several months. One study of 22 children found that the average duration of PLEVA was approximately 1.6 months; however, the duration may be longer in adults. Some people may experience episodes of the condition on and off for years.
The prognosis tends to be worse in people who develop a rare variant of PLEVA called Febrile Ulceronecrotic Mucha-Haberman Disease. For more information on this condition, please click here.
Last updated: 9/15/2015
We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please