The Medication(s) listed below have been approved by the Food & Drug Administration (FDA) as orphan products for treatment of this condition. There may be other products available that are not considered orphan products.

• Midodrine HCl (Brand name: Amatine) - Manufactured by Takeda Development Center
  FDA-approved indication: Treatment of patients with symptomatic orthostatic hypotension
  National Library of Medicine Drug Information Portal Medline Plus Health Information

  Learn more about Pure autonomic failure

• Droxidopa (Brand name: Northera) - Manufactured by Chelsea Therapeutics, Inc.
  FDA-approved indication: February 2014, Droxidopa (Northera) was approved for the treatment of orthostatic dizziness, lightheadedness, or the "feeling that you are about to black out" in adult patients with symptomatic neurogenic orthostatic hypotension caused by primary autonomic failure (Parkinson's disease, multiple system atrophy, and pure autonomic failure), dopamine beta-hydroxylase deficiency, and non-diabetic autonomic neuropathy.
  National Library of Medicine Drug Information Portal Medline Plus Health Information

  Learn more about Pure autonomic failure