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Diseases

Genetic and Rare Diseases Information Center (GARD)

Opsoclonus-myoclonus syndrome


Other Names for this Disease
  • Polymyoclonus infantile
  • Infantile polymyoclonus
  • Opsoclonus myoclonus syndrome
  • OMS
  • Kinsbourne syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Newline Maker

How might opsoclonus myoclonus syndrome be treated?

Treatment for opsoclonus myoclonus syndrome may include corticosteroids or ACTH (adrenocorticotropic hormone), human intravenous immunoglobulins (IVIG), or immunosuppressive agents.[1][2] In cases where there is a tumor present, treatment such as surgery for tumor removal, chemotherapy or radiation may be required.[1] In many cases, a combination of the above yields the best result.

Sleep problems and associated rage attacks may respond to trazodone. Some adults with paraneoplastic OMA do not have more neurologic symptoms when the removing or after treatment the neuroblastoma. Adults may be less likely to respond to immunological treatment compared with children.[3] 
Last updated: 1/27/2016

References
  1. NINDS Opsoclonus Myoclonus Information Page. National Institute of Neurological Disorders and Stroke (NINDS). 2007; http://www.ninds.nih.gov/disorders/opsoclonus_myoclonus/opsoclonus_myoclonus.htm.
  2. Pranzatelli MR. What is the Opsoclonus-Myoclonus Syndrome?. Opsoclonus-Myoclonus U.S.A. And International web site. http://www.omsusa.org/pranzatelli-Brochure1.htm.
  3. Dalmau J & Rosenfeld MR. Opsoclonus myoclonus ataxia. UpToDate. June 19, 2015; http://www.uptodate.com/contents/opsoclonus-myoclonus-ataxia?source=search_result&search=opsoclonus+myoclonus+syndrome&selectedTitle=1~17#H24048217.


GARD Video Tutorial

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Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Opsoclonus-myoclonus syndrome. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • Polymyoclonus infantile
  • Infantile polymyoclonus
  • Opsoclonus myoclonus syndrome
  • OMS
  • Kinsbourne syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.