Other Names for this Disease
- Chronic recurrent multifocal osteomyelitis, congenital
- Dyserythropoietic anemia, and neutrophilic dermatosis
- Congenital dyserythropoietic anemia and chronic recurrent multifocal osteomyelitis
- CDA and CRMO
- Chronic recurrent multifocal osteomyelitis - congenital dyserythropoietic anemia - neutrophilic dermatosis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
On this page
Majeed syndrome is caused by mutations in the LPIN2 gene. This gene provides instructions for making a protein called lipin-2. Researchers believe that this protein may play a role in the processing of fats. It may also be involved in controlling inflammation and play a role in cell division. Mutations in the LPIN2 gene alter the structure and function of lipin-2. It is unclear how these genetic changes lead to bone disease, anemia, and inflammation of the skin in people with Majeed syndrome.
Last updated: 10/31/2013
- Majeed syndrome. Genetics Home Reference (GHR). August 2009; http://ghr.nlm.nih.gov/condition/majeed-syndrome. Accessed 10/31/2013.