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Diseases

Genetic and Rare Diseases Information Center (GARD)

Osteogenesis imperfecta


Other Names for this Disease
  • OI
  • Brittle bone disease
  • Vrolik disease
  • Fragilitas ossium
  • Glass bone disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Your Questions Answered


4 question(s) from the public on this disease have been answered. Submit a new question.
  • Can a person have osteogensis imperfecta (OI) without having any fractures? Can people with osteogenesis imperfecta (OI) have bone pain in areas where a fracture wasn't present? Click here for answer

  • I am a restorative dentist. I have an eight year old patient diagnosed with osteogenesis imperfecta. Her brother does not have the disease. Her parents also do not have the disease. But, her mother's father has the disease. What could be the inheritance pattern? Click here for answer

  • I have a cousin with osteogenesis imperfecta. Neither of his parents has the dominant gene. Is there a genetic test that can be done to determine whether I am a carrier? Click here for answer

  • What are the chances of passing osteogenesis imperfecta on to a child while pregnant? Can a vaginal delivery be perfomed or will a C-section be necessary? Click here for answer

Other Names for this Disease
  • OI
  • Brittle bone disease
  • Vrolik disease
  • Fragilitas ossium
  • Glass bone disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.