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duodenum biopsy results, but with an increased number of mast cells in the colonic mucosa (the innermost layer of the colon). The increase in mast cells is not associated with systemic or cutaneous mastocytosis. It is unclear whether the accumulation of mast cells is a response to, or cause of, the mucosal inflammation that causes the symptoms of the condition. Most individuals with this condition respond well to drugs affecting mast cell function.Mastocytic enterocolitis is a term describing the condition of chronic, intractable diarrhea in people with normal colon or
Last updated: 5/29/2014
- Ogilvie-McDaniel C, Blaiss M, Osborn FD, Carpenter J. Mastocytic enterocolitis: a newly described mast cell entity. Ann Allergy Asthma Immunol. December 2008; 101(6):645-646.
- Jakate S, Demeo M, John R, Tobin M, Keshavarzian A.. Mastocytic enterocolitis: increased mucosal mast cells in chronic intractable diarrhea. Arch Pathol Lab Med. 2006 Mar; http://www.ncbi.nlm.nih.gov/pubmed/16519565. Accessed 9/19/2012.
- The Centers for Disease Control and Prevention (CDC) provides information on chronic diarrhea. The CDC is recognized as the lead federal agency for developing and applying disease prevention and control, environmental health, and health promotion and education activities designed to improve the health of the people of the United States.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Mastocytic enterocolitis. Click on the link to view a sample search on this topic.