Selective IgA deficiency
Other Names for this Disease
- Immunoglobulin A, selective deficiency of
- IgA, selective deficiency of
- Gamma-A-globulin, selective deficiency of
- Immunoglobulin A deficiency 1
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autosomal dominant inheritance, others of autosomal recessive inheritance.Selective IgA deficiency refers to the complete or severe deficiency of IgA. This deficiency makes one more prone to infections, allergies, diarrhea, and autoimmune diseases. It is the most common type of primary immunodeficiency and is caused by a lack of mature B-lymphocytes. Why the B-lymphocytes fail to mature and produce IgA is not clear. Familial occurrence has been reported in the medical literature, some cases were suggestive of
Last updated: 8/19/2009
- Selective IgA deficiency. Primary Immunodeficiency Resource Center. http://www.info4pi.org/aboutPI/index.cfm?section=aboutPI&content=syndromes&area=2&CFID=34984195&CFTOKEN=54477486. Accessed 8/19/2009.
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- The National Primary Immunodeficiency Resource Center has an information page on this topic. Click on the link above to view the information page.
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- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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