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 The cause of aquagenic pruritus is unknown; however, familial cases have been described. It may be a symptom of polycythemia vera or other diseases. Therefore, a thorough evaluation should be performed to rule out other more serious conditions. Overall, treatment is a challenge. Antihistamines, UVB phototherapy, PUVA therapy and various medications have been tried with varying success.Aquagenic pruritus is a condition in which contact with water of any temperature causes intense itching without any visible skin changes. The symptoms may begin immediately after contact with water and can last for an hour or more.
Last updated: 6/20/2016
- Sekar CS, Srinivas CR & Jacob S. Aquagenic pruritus: beneath water "lies". Indian J Dermatol. 2011 Jul; 56(4):446-7. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179019/.
- Cao T, Yong AA, Tan KB, Tey HL. Idiopathic aquagenic pruritus: pathogenesis and effective treatment with atenolol.. Dermatol Ther. 2015 May-Jun; 28(3):118-21. http://www.ncbi.nlm.nih.gov/pubmed/25640024.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Aquagenic pruritus. Click on the link to view a sample search on this topic.