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Diseases

Genetic and Rare Diseases Information Center (GARD)

Klippel Feil syndrome


Other Names for this Disease
  • Cervical vertebral fusion
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Treatment

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How might Klippel-Feil syndrome be treated?

There is no cure for Klippel Feil syndrome (KFS); treatment is generally symptomatic and supportive. Management depends on the features and severity in each person, and can be life-long. Careful evaluation, consistent follow-up, and coordination with various specialists are needed to improve outcome and make sure that no related diagnosis is missed.[1]

There are various conservative therapies available, including the use of cervical collars, braces, traction, physical therapy, non-steroidal anti-inflammatory drugs (NSAIDs), and various pain medications.[2][3] However, for many people with KFS, symptoms are progressive due to degenerative changes that occur in the spine.[1]

Surgery may be indicated for a variety of reasons, including persistent pain; neurologic deficits; cervical or craniocervical instability; constriction of the spinal cord; or to correct severe scoliosis.[2] Some people with KFS may need surgery to repair other skeletal abnormalities, or those related to the heart, kidneys, ears, eyes, or other parts of the body.[3]

Those at an increased risk for neurological complications should be regularly monitored by their health care providers and may be advised to avoid activities that could lead to trauma or injury to cervical vertebrae.[3]
Last updated: 9/30/2015

References
  1. Thomas R Lewis. Klippel-Feil Syndrome. Medscape Reference. January 26, 2015; http://emedicine.medscape.com/article/1264848-overview#showall.
  2. Klippel-Feil Syndrome Information Page. NINDS. September 16, 2011; http://www.ninds.nih.gov/disorders/klippel_feil/klippel_feil.htm.
  3. Klippel-Feil Syndrome. NORD. 2011; http://rarediseases.org/rare-diseases/klippel-feil-syndrome/.


GARD Video Tutorial

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    Finding Treatment Information

Management Guidelines

  • Project OrphanAnesthesia is a project whose aim is to create peer-reviewed, readily accessible guidelines for patients with rare diseases and for the anesthesiologists caring for them. The project is a collaborative effort of the German Society of Anesthesiology and Intensive Care, Orphanet, the European Society of Pediatric Anesthesia, anesthetists and rare disease experts with the aim to contribute to patient safety.

Clinical Trials & Research for this Disease

  • The Centers for Mendelian Genomics program is working to discover the causes of rare genetic disorders. For more information about applying to the research study, please visit their website.
Other Names for this Disease
  • Cervical vertebral fusion
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.