Other Names for this Disease
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white matter of the brain due to softening of the brain tissue. It can affect fetuses or newborns, and premature babies are at the greatest risk of the disorder. PVL is caused by a lack of oxygen or blood flow to the area around the ventricles of the brain, which results in the death of brain tissue. Although babies with PVL generally have no apparent signs or symptoms of the disorder at delivery, they are at risk for motor disorders, cerebral palsy, delayed mental development, coordination problems, and vision and hearing impairments.There is no cure for PVL. Treatment is generally supportive. Prognosis is dependent on the extent of damage to the ventricles.Periventricular leukomalacia (PVL) is a brain injury disorder characterized by the death of the
Last updated: 3/22/2016
- NINDS Periventricular Leukomalacia Information Page. National Institute of Neurological Disorders and Stroke (NINDS). March 15, 2016; http://www.ninds.nih.gov/disorders/periventricular_leukomalacia/periventricular_leukomalacia.htm.
- Terence Zach. Pediatric Periventricular Leukomalacia. Medscape. January 16, 2015; http://emedicine.medscape.com/article/975728-overview.
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- The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
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- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Periventricular leukomalacia. Click on the link to view a sample search on this topic.