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Your QuestionHow might scleroderma be treated?
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Localized scleroderma can be divided in:
- Diffuse cutaneous systemic sclerosis
- Limited cutaneous systemic sclerosis (which includes CREST syndrome)
- Limited Systemic Sclerosis (or systemic sclerosis sine scleroderm).
The following medications may be used to treat scleroderma:
- Immune suppressing medications (methotrexate, Cytoxan)
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Drugs for heartburn or swallowing problems (proton pump inhibitors)
- Prokinetic agents to speeding the movement of food through the stomach and intestines
- Antibiotics to address malabsorption syndrome
- Blood pressure medications (particularly ACE inhibitors) for high blood pressure or kidney problems
- Antihistamines and skin moisturizers to relieve itching
- Medicines to prevent (e.g., Bosentan) or treat (e.g., iloprost) ulcers
- Medicines to improve breathing (See: Pulmonary hypertension)
- Medicines to treat lung scarring (e.g., cyclophosphamide)
- Medications to treat Raynaud's phenomenon (e.g., nifedipine, iloprost)
More detailed information regarding the treatment of scleroderma can be accessed through MedScape.
- Borigini MJ. Scleroderma. MedlinePlus. 2014; http://www.nlm.nih.gov/medlineplus/ency/article/000429.htm.
- Scleroderma. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). 2010; http://www.niams.nih.gov/Health_Info/Scleroderma/default.asp. Accessed 10/11/2010.
- Denton CP. Overview and classification of scleroderma disorders. UpToDate. January 9, 2015; http://www.uptodate.com/contents/overview-and-classification-of-scleroderma-disorders.
- Localized scleroderma. Orphanet. July, 2010; http://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=12000.
- Scleroderma. MayoClinic.com. 2008; http://www.mayoclinic.com/print/scleroderma/DS00362/DSECTION=all&METHOD=print. Accessed 10/11/2010.
- Denton CP. Overview of the treatment and prognosis of systemic sclerosis (scleroderma) in adults. In: Basow M, ed. UpToDate. Waltham, MA: UpToDate; 2014; Accessed 10/28/2014.
- Scleroderma Program. University of Michigan Health System. http://www.med.umich.edu/scleroderma/patients/guidelines.htm. Accessed 10/28/2014.