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Diseases

Genetic and Rare Diseases Information Center (GARD)

Gamma heavy chain disease


Other Names for this Disease
  • IgG heavy chain disease
  • Franklin disease
  • Gamma heavy chain deposition disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

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How might gamma heavy chain disease be treated?

People with symptoms may respond to chemotherapy drugs, corticosteroids, and radiation therapy.[1][2] Commonly used chemotherapeutic agents include cyclophosphamide, prednisone, vincristine, chlorambucil and doxorubicin. Patients are most commonly treated and followed by oncologists and/or hematologists.[3]

Additional information about treatment of gamma heavy chain disease can be found through PubMed, a searchable database of biomedical journal articles. Although not all of the articles are available for free online, most articles listed in PubMed have a summary available. To obtain the full article, contact a medical/university library or your local library for interlibrary loan. You can also order articles online through the publisher's Web site. Using "gamma heavy chain disease [ti] AND treatment" as your search term should help you locate articles. Use the advanced search feature to narrow your results. Click here to view a search.

Last updated: 7/25/2010

References
  1. Heavy chain diseases. Merck Manual for Healthcare Professionals. July 2008; http://www.merck.com/mmpe/sec11/ch144/ch144b.html. Accessed 7/25/2010.
  2. Heavy chain diseases. Merck Manuals Online Medical Library. July 2008; http://www.merck.com/mmhe/sec14/ch175/ch175e.html. Accessed 7/25/2010.
  3. Brick W, Faguet GB, Burgess R. Heavy Chain Disease, Gamma. eMedicine Journal. April 15, 2009; http://emedicine.medscape.com/article/200675-overview. Accessed 7/25/2010.


Other Names for this Disease
  • IgG heavy chain disease
  • Franklin disease
  • Gamma heavy chain deposition disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.