Immunoglobulin G deficiency
* Not a rare disease
Other Names for this Disease
- IgG deficiency
- IgG subclass deficiency
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antibodies. There are four different subclasses of IgG: IgG1, IgG2, IgG3, and IgG4. People with IgG deficiency may have a decreased amount of one or more of the IgG subclasses. When people also have a shortage of other types of antibodies, they are said to have a combined immunodeficiency. Individuals with IgG deficiency may have an increased susceptibility to infection, but the symptoms of this condition are variable. Some people never experience any symptoms. Treatment may involve antibiotics and intravenous (IV) immunoglobulin.Immunoglobulin G (IgG) deficiency is a condition that involves the immune system and is characterized by a shortage of type G
Last updated: 11/11/2008
- Vafaie J. Immunoglobulin G deficiency. eMedicine Journal. Mar 22, 2005; http://www.emedicine.com/med/TOPIC1161.HTM. Accessed 11/11/2008.
- IgG Subclass Deficiency. National Primary Immunodeficiency Resource Center. http://www.info4pi.org/patienttopatient/index.cfm?section=patienttopatient&content=syndromes&area=8. Accessed 11/11/2008.
- The Immune Deficiency Foundation Patient and Family Handbook for Primary Immunodeficiencies contains information on many primary immunodeficiencies, including IgG subclass deficiency.
- The Immune Deficiency Foundation produces the Clinical Focus on Primary Immunodeficiencies. It is a newletter designed for health care professionals and focuses on topics relevant to primary immunodeficiency diseases. One issue of the publication focused on IgG Subclass Deficiency.
- The National Primary Immunodeficiency Resource Center provides information on IgG subclass deficiency.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Immunoglobulin G deficiency. Click on the link to view a sample search on this topic.