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Diseases

Genetic and Rare Diseases Information Center (GARD)

Autosomal dominant polycystic kidney disease

*

* Not a rare disease

Other Names for this Disease
  • ADPKD
  • Polycystic kidney disease, adult type
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

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What is the treatment for autosomal dominant polycystic kidney disease (ADPKD)?

Although a cure for ADPKD is not available, treatment can ease symptoms and prolong life.[1] Treatment is aimed at treating both kidney and non-kidney symptoms. Pain in the area of the kidneys is treated as needed with pain medications, and for chronic pain, with antidepressants. When standard methods of treating kidney pain do not work, fluid may be removed from the kidney cysts. When kidney function starts to decline, treatment is aimed at slowing down the progression to kidney failure. This involves controlling high blood pressure, restricting protein in the diet, controlling build up of acid (acidosis) and preventing elevated levels of phosphate (hyperphosphatemia). When individuals with ADPKD develop renal failure, they need to have dialysis or a kidney transplant.[2]
Last updated: 1/19/2010

References
  1. Polycystic Kidney Disease. National Kidney and Urologic Diseases Information Clearinghouse. November 2007; http://kidney.niddk.nih.gov/kudiseases/pubs/polycystic/. Accessed 6/22/2011.
  2. Learning About Autosomal Dominant Polycystic Kidney Disease. National Human Genome Research Institute (NHGRI). April 18, 2013; http://www.genome.gov/20019622. Accessed 10/5/2015.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information

Management Guidelines

  • GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions.

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Autosomal dominant polycystic kidney disease. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • ADPKD
  • Polycystic kidney disease, adult type
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.