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Diseases

Genetic and Rare Diseases Information Center (GARD)

Goblet cell carcinoid


Other Names for this Disease
  • GCC
  • Goblet cell adenocarcinoid
  • Goblet cell carcinoma
  • Goblet cell tumor
  • Mucinous carcinoid
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Goblet cell carcinoid (GCC) is a rare neuroendocrine tumor that almost always occurs in the appendix.[1] It is usually diagnosed in a person's 50's.[2] People with this tumor may develop acute appendicitis, abdominal pain, and a lump. In about half of women, the tumor has already spread to the ovary by the time it is diagnosed. Prognosis largely depends on the size of the tumor and whether it has spread to other parts of the body. About 76% of people with a GCC are alive five years after they are diagnosed. Treatment involves surgery to remove the tumor. Depending on how much the tumor has spread, surgeons may remove the appendix, part of the colon, or the ovaries in women. Some people will have chemotherapy after surgery.[3]
Last updated: 5/1/2015

References

  1. Paromita Roy and Runjan Chetty. Goblet cell carcinoid tumors of the appendix: An overview. World J Gastrointest Oncol. June 15, 2010; 2(6):251–258. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998842/. Accessed 5/1/2015.
  2. Gastrointestinal Carcinoid Tumors Treatment (PDQ®): Appendiceal Carcinoids. National Cancer Institute. February 15, 2015; http://www.cancer.gov/cancertopics/pdq/treatment/gastrointestinalcarcinoid/HealthProfessional/page8. Accessed 5/1/2015.
  3. Information for people affected by Goblet Cell Carcinomas. NET Patient Foundation. July 2014; http://www.netpatientfoundation.org/wp-content/uploads/020-NPF-GOBLET-CELL-CARCINOMA-v6.pdf. Accessed 5/1/2015.
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Basic Information

  • The American Cancer Society has an information page on gastrointestinal carcinoid tumor. Click on American Cancer Society to view the information page.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.
  • The Carcinoid Cancer Foundation, Inc. has an information page on carcinoid tumors and related neuroendocrine tumors. Click on Carcinoid Cancer Foundation, Inc. to view the information page.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
    Orphanet
    Orphanet
Other Names for this Disease
  • GCC
  • Goblet cell adenocarcinoid
  • Goblet cell carcinoma
  • Goblet cell tumor
  • Mucinous carcinoid
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.