See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
nervous system. There are three types of neurofibromatosis that are each associated with unique signs and symptoms:Neurofibromatosis (NF) is a genetic condition that causes tumors to develop in the
- Neurofibromatosis type 1 (NF1) causes skin changes (cafe-au-lait spots, freckling in armpit and groin area); bone abnormalities; optic gliomas; and tumors on the nerve tissue or under the skin. Signs and symptoms are usually present at birth.
- Neurofibromatosis type 2 (NF2) causes acoustic neuromas; hearing loss; ringing in the ears; poor balance; brain and/or spinal tumors; and cataracts at a young age. It often starts in the teen years.
Last updated: 7/27/2015
- Learning About Neurofibromatosis. National Human Genome Research Institute. March 2014; http://www.genome.gov/14514225.
- Neurofibromatosis. MedlinePlus. 2009; http://www.nlm.nih.gov/medlineplus/neurofibromatosis.html. Accessed 2/10/2010.
- Neurofibromatosis Fact Sheet. National Institute of Neurological Disorders and Stroke. April 2014; http://www.ninds.nih.gov/disorders/neurofibromatosis/detail_neurofibromatosis.htm.
- DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The National Human Genome Research Institute's (NHGRI) mission encompasses a broad range of studies aimed at understanding the structure and function of the human genome and its role in health and disease. Click on the link to view the information page on this topic.
- The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
- MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- The Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Neurofibromatosis. Click on the link to view a sample search on this topic.