Other Names for this Disease
- Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
- Dementia, hereditary multi-infarct type
- Familial vascular leukoencephalopathy
- Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
On this page
There is currently no treatment for CADASIL that is proven to be effective. While antiplatelet treatment is often used, it is also not proven to be useful. Migraine should be treated both symptomatically and prophylactically (with preventative methods), depending on the frequency of symptoms. When hypertension, diabetes or hypercholesterolemia (high cholesterol) are also present, they should be treated. Supportive care, including practical help, emotional support, and counseling, is useful for affected people and their families. Smoking increases the risk of stroke, so affected people who smoke should quit.
Last updated: 10/19/2015
- Julie Rutten and Saskia AJ Lesnik Oberstein. CADASIL. GeneReviews. February 26, 2015; http://www.ncbi.nlm.nih.gov/books/NBK1500/.
- GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions.
- Project OrphanAnesthesia is a project whose aim is to create peer-reviewed, readily accessible guidelines for patients with rare diseases and for the anesthesiologists caring for them. The project is a collaborative effort of the German Society of Anesthesiology and Intensive Care, Orphanet, the European Society of Pediatric Anesthesia, anesthetists and rare disease experts with the aim to contribute to patient safety.
- ClinicalTrials.gov lists trials that are studying or have studied CADASIL. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.