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neural tube defect in which both the brain and spinal cord remain open; both anencephaly and spina bifida (from the cervical region to the lumbar or sacral region of the spine) are present. Fetuses with craniorachischisis often miscarry during pregnancy or die shortly after birth. The cause is thought to be multifactorial, which means that a combination of genetic and non-genetic factors play a role.Craniorachischisis is the most severe type of
Last updated: 11/5/2013
- Craniorachischisis. Orphanet. January, 2010; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=EN&Expert=63260. Accessed 11/4/2013.
- Johnson KM, Suarez L, Felkner MM, Hendricks K. Prevalence of craniorachischisis in a Texas-Mexico border population. Birth Defects Res A Clin Mol Teratol. February, 2004; 70(2):92-94. Accessed 11/5/2013.
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