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 They tend to occur in the lower part of the spinal column and are usually considered to be benign, low-grade or grade I tumors. The age of diagnosis ranges from 6 to 82 years. Symptoms of an ependymoma are related to the location and size of the tumor and may include nausea, vomiting, headache, pain, numbness, bowel or bladder symptoms, and various other signs and symptoms. The cause of ependymomas is unknown. They are known to recur locally (more commonly in individuals diagnosed in childhood). Treatment may vary depending on the location, grade, and whether the tumor has spread to the spine, but typically includes aggressive surgery. Management may also include chemotherapy and radiation therapy.Myxopapillary ependymoma (MEPN) is a slow-growing ependymoma (a type of glioma, which is a tumor that arises from the supportive tissue of the brain and spinal cord).
Last updated: 4/13/2015
- Valerie N Barton et al. Unique Molecular Characteristics of Pediatric Myxopapillary Ependymoma. Brain Pathology. May 2010; 20(3):560-570. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871180/?tool=pubmed. Accessed 4/7/2011.
- Ependymoma. American Brain Tumor Association. http://www.abta.org/siteFiles/pdflibrary/ABTA_Ependymoma_Pamph_7%202%2010.pdf. Accessed 4/7/2011.
- Jeffrey N Bruce. Ependymoma. Medscape. January 26, 2009; http://www.medscape.com/viewarticle/465375_2. Accessed 4/7/2011.
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- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Myxopapillary ependymoma. Click on the link to view a sample search on this topic.