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Diseases

Genetic and Rare Diseases Information Center (GARD)

Mucoepidermoid carcinoma


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Overview

Mucoepidermoid carcinoma is a type of cancer of the salivary glands.  Salivary gland cancer is diagnosed in 2-3 individuals per 100,000 people each year, and 30-35% of these are mucoepidermoid carcinomas.[1][2]   Mucoepidermoid carcinoma develops when a cell randomly acquires changes (mutations) in genes that regulate how the cell divides such that it begins to grow quickly, forming a cluster of cells (a mass or lump).[1]  The earliest signs of a mucoepidermoid carcinoma may include a lump in the face, neck, or mouth; numbness, weakness, or pain in part of the face; or difficulty swallowing.  Treatment often begins with surgery to remove the entire tumor.  In some cases, radiation therapy and/or chemotherapy may be used after surgery to ensure that no cancer cells remain in the body.[2]
Last updated: 6/18/2013

References

  1. Chandana SR, Conley BA. Salivary gland cancers: current treatments, molecular characteristics and new therapies.. Expert Review of Anticancer Therapy. 2008; 8:645-652. http://www.ncbi.nlm.nih.gov/pubmed/18402531. Accessed 8/3/2011.
  2. American Cancer Society. Salviary Gland Cancer. Learn About Cancer. 2011; http://www.cancer.org/Cancer/SalivaryGlandCancer/DetailedGuide/salivary-gland-cancer-what-is-salivary-gland-cancer. Accessed 8/3/2011.
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In Depth Information

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  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
Related Diseases
  • Salivary gland type cancer of the breast
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.