Progressive transformation of germinal centers
Other Names for this Disease
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lymphadenopathy). Typically, only one lymph node is affected, though PTGC can involve multiple lymph nodes. The neck is the most common location of affected lymph nodes, but PTGC may also affect lymph nodes in the groin and armpits. Adults are more frequently affected than children, but children have a higher chance of developing PTGC multiple times (recurrence). PTGC is not considered a precancerous condition, though it has been associated with Hodgkin lymphoma.Progressive transformation of germinal centers is a condition in which a lymph node becomes very enlarged (
Last updated: 4/24/2013
- Hicks J, Flaitz C. Progressive transformation of germinal centers: review of histopathologic and clinical features. International Journal of Pediatric Otorhinolaryngology. 2002; 65:195-202. http://www.ncbi.nlm.nih.gov/pubmed/12242134. Accessed 4/23/2013.
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- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.