Progressive transformation of germinal centers
Other Names for this Disease
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Because progressive transformation of germinal centers (PTGC) is considered a benign condition and usually has no symptoms other than the enlarged lymph node, no treatment is necessary. The enlarged lymph node may stay the same size or shrink over time. Affected individuals should have regular follow-up visits with their physician; a biopsy should be taken of any new enlarged lymph node because PTGC is associated with Hodgkin lymphoma in some individuals.
Last updated: 4/24/2013
- Brown JR, Skarin AT. Clinical mimics of lymphoma. The Oncologist. 2004; 9:406-416. http://www.ncbi.nlm.nih.gov/pubmed/15266094. Accessed 4/23/2013.
- Hicks J, Flaitz C. Progressive transformation of germinal centers: review of histopathologic and clinical features. International Journal of Pediatric Otorhinolaryngology. 2002; 65:195-202. http://www.ncbi.nlm.nih.gov/pubmed/12242134. Accessed 4/23/2013.
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