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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Bilateral frontoparietal polymicrogyria


Other Names for this Disease
  • BFPP
  • Cerebellar ataxia with neuronal migration defect
Related Diseases
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Symptoms

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What are the signs and symptoms of Bilateral frontoparietal polymicrogyria?

The signs and symptoms of bilateral frontoparietal polymicrogyria vary but may include:[1][2]
  • Moderate to severe intellectual disability
  • Developmental delay
  • Seizures
  • Dysconjugate gaze (eyes that are not aligned)
  • Ataxia
  • Strabismus
  • Increased muscle tone
  • Finger dysmetria (difficulty controlling speed, distance and/or power of movements)
Last updated: 6/7/2015

The Human Phenotype Ontology provides the following list of signs and symptoms for Bilateral frontoparietal polymicrogyria. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms.

Signs and Symptoms Approximate number of patients (when available)
Ankle clonus -
Autosomal recessive inheritance -
Babinski sign -
Broad-based gait -
Cerebellar hypoplasia -
Cerebral dysmyelination -
Esotropia -
Exotropia -
Frontoparietal polymicrogyria -
Hyperreflexia -
Hypertonia -
Hypoplasia of the brainstem -
Intellectual disability -
Nystagmus -
Polymicrogyria, anterior to posterior gradient -
Seizures -
Truncal ataxia -

Last updated: 7/1/2015

The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature.

The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined.

Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.


References
  1. POLYMICROGYRIA, BILATERAL FRONTOPARIETAL; BFPP. OMIM. April 2014; http://omim.org/entry/606854.
  2. Chang B, Walsh CA, Apse K & Bodell A. Polymicrogyria Overview. Gene Reviews. August 6, 2007; http://www.ncbi.nlm.nih.gov/books/NBK1329/. Accessed 3/9/2015.


Other Names for this Disease
  • BFPP
  • Cerebellar ataxia with neuronal migration defect
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.