Bilateral generalized polymicrogyria
Other Names for this Disease
- Bilateral generalised polymicrogyria
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 This is the most widespread form of polymicrogyria and typically affects the entire surface of the brain. Signs and symptoms include severe intellectual disability, problems with movement, and seizures that are difficult or impossible to treat. While the exact cause of bilateral generalized polymicrogyria is not fully understood, it is thought to be due to improper brain development during embryonic growth. Most cases appear to follow an autosomal recessive pattern of inheritance. Treatment is based on the signs and symptoms present in each person.Bilateral generalized polymicrogyria is a rare neurological disorder that affects the cerebral cortex (the outer surface of the brain).
Last updated: 6/15/2015
- Polymicrogyria. Genetics Home Reference. June 2009; http://ghr.nlm.nih.gov/condition/polymicrogyria. Accessed 6/15/2015.
- Chang B, Walsh CA, Apse K, Bodell A. Polymicrogyria Overview. GeneReviews. August 6, 2007; http://www.ncbi.nlm.nih.gov/books/NBK1329/. Accessed 6/15/2015.
- Polymicrogyria. Cortical Foundation. http://cortfoundation.org/cms/get-informed/types-of-malformations/polymicrogyria/. Accessed 6/15/2015.
- Genetics Home Reference (GHR) contains information on Bilateral generalized polymicrogyria. This website is maintained by the National Library of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- Chang BS et al., Bilateral generalized polymicrogyria (BGP): A distinct syndrome of cortical malformation Neurology. 2004; 62:1722-1728.