Logopenic progressive aphasia
Other Names for this Disease
- Logopenic primary progressive aphasia
- Logopenic variant PPA
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aphasia). It is a type of primary progressive aphasia (PPA). Affected individuals have slow, hesitant speech due to difficulty retrieving the correct words, names, or numbers. Difficulty with phase and sentence repetition are additionally present. Speech is typically well articulated and grammatically correct with good single-word comprehension. But over time, affected individuals may have trouble understanding long or complex verbal information, due to problems holding onto lengthy information that they hear. Language difficulties associated with LPA are due to shrinking, or atrophy, in the left posterior temporal cortex and inferior parietal lobule. Click here to view an image of the lobes of the brain.Logopenic progressive aphasia (LPA) is a type of dementia characterized by language disturbance, including difficulty making or understanding speech (
Last updated: 1/18/2013
- Primary Progressive Aphasia. UCSF Memory and Aging Center. February 2011; http://memory.ucsf.edu/education/diseases/ppa. Accessed 9/14/2011.
- Donna C. Tippett, Argye E. Hillis,Kyrana Tsapkini. Treatment of Primary Progressive Aphasia. Curr Treat Options Neurol.. August 2015; 17(8):362. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600091/.
- M.L. Gorno-Tempini,A.E. Hillis, S. Weintraub, A. Kertesz, M. Mendez, S.F. Cappa, J.M. Ogar, J.D. Rohrer, S. Black, B.F. Boeve, F. Manes, N.F. Dronkers, R. Vandenberghe, K. Rascovsky, K. Patterson, B.L. Miller, D.S. Knopman, J.R. Hodges, M.M. Mesulam, M. Grossman. Classification of primary progressive aphasia and its variants. Neurology. March 2011; 76(11):1006-1014. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059138/.
- The National Aphasia Association provides information on primary progressive aphasia and Logopenic progressive aphasia
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Logopenic progressive aphasia. Click on the link to view a sample search on this topic.