Other Names for this Disease
- MAP syndrome
- Autosomal recessive familial adenomatous polyposis
- Colorectal adenomatous polyposis
- Familial polyposis coli
- Familial adenomatous polyposis
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Mutations in the MYH gene cause MYH-associated polyposis. Mutations in this gene prevent cells from correcting mistakes that are made when DNA is copied (DNA replication) in preparation for cell division. As these mistakes build up in a person's DNA, the likelihood of cell overgrowth increases, leading to colon polyps and the possibility of colon cancer.
Last updated: 6/28/2011
- Familial adenomatous polyposis. Genetics Home Reference (GHR). April 2008; http://ghr.nlm.nih.gov/condition/familial-adenomatous-polyposis. Accessed 6/28/2011.