Acquired pure red cell aplasia
Other Names for this Disease
- Idiopathic pure red cell aplasia
- Adult pure red cell aplasia
- Acquired PRCA
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bone marrow disorder characterized by a reduction of red blood cells (erythrocytes) produced by the bone marrow. Signs and symptoms may include fatigue, lethargy, and/or abnormal paleness of the skin (pallor) due to the anemia the caused by the disorder. In most cases, the cause of acquired PRCA is unknown (idiopathic). In other cases it may occur secondary to autoimmune disorders, tumors of the thymus gland (thymomas), hematologic cancers, solid tumors, viral infections, or certain drugs. Treatment depends on the cause of the condition (if known) but often includes transfusions for individuals who are severely anemic and have cardiorespiratory failure.Acquired pure red cell aplasia (PRCA) is a
Last updated: 12/14/2011
- Pure Red Cell Aplasia, Acquired. NORD. August 7, 2007; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/506/viewAbstract. Accessed 12/14/2011.
- Paul Schick. Pure Red Cell Aplasia. eMedicine. October 25, 2011; http://emedicine.medscape.com/article/205695-overview. Accessed 12/14/2011.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
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- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Acquired pure red cell aplasia. Click on the link to view a sample search on this topic.