49, XXXYY syndrome
Other Names for this Disease
- XXXYY syndrome
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chromosome abnormality that occurs when a male inherits two extra copies of the X chromosome and one extra copy of the Y chromosome. The condition is extremely rare with only a handful of cases reported in the medical literature. Signs and symptoms associated with these cases include severe intellectual disability, distinctive facial features, normal to tall stature, gynecomastia, hypogonadism, and behavioral abnormalities. 49, XXXYY syndrome is likely caused by a mistake (called nondisjunction) that occurs at conception or during the formation of the sperm and/or egg. Treatment is based on the signs and symptoms present in each person.49, XXXYY syndrome is a
Last updated: 5/17/2016
- The Children's Hospital Colorado offers an information page on 49, XXXYY syndrome. Please click on the link to access this resource.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss 49, XXXYY syndrome. Click on the link to view a sample search on this topic.