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Diseases

Genetic and Rare Diseases Information Center (GARD)

Progressive bulbar palsy


Other Names for this Disease
  • Progressive bulbar atrophy
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Overview

Progressive bulbar palsy involves the brain stem. The brain stem is the part of the brain needed for swallowing, speaking, chewing, and other functions. Signs and symptoms of progressive bulbar palsy include difficulty swallowing, weak jaw and facial muscles, progressive loss of speech, and weakening of the tongue. Additional symptoms include less prominent weakness in the arms and legs, and outbursts of laughing or crying (called emotional lability).[1]

Progressive bulbar palsy is considered a variant form of amyotrophic lateral sclerosis (ALS).[1][2] Many people with progressive bulbar palsy later develop ALS. While there is no cure for progressive bulbar palsy or for ALS, doctors can treat symptoms.
Last updated: 7/29/2015

References

  1. Motor Neuron Diseases Fact Sheet. National Institute of Neurological Disorders and Stroke (NINDS). 2010; http://www.ninds.nih.gov/disorders/motor_neuron_diseases/detail_motor_neuron_diseases.htm. Accessed 3/9/2010.
  2. Elman L, McCluskey L. Clinical features of amyotrophic lateral sclerosis and other forms of motor neuron disease. In: Shefner JM ed.,. UpToDate. Waltham, MA: UpToDate; 2015; Accessed 7/29/2015.
  3. Elman LB, McCluskey L. Diagnosis of amyotrophic lateral sclerosis and other forms of motor neuron disease. In: Basow, DS (Ed). UpToDate. Waltham, MA: UpToDate; 2015; Accessed 7/29/2015.
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Basic Information

In Depth Information

  • The Dutch Neuromuscular Research Center (ISNO) offers a detailed summary on progressive bulbar palsy. Click on the link to view the article.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Progressive bulbar palsy. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Progressive bulbar atrophy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.