Autoimmune polyglandular syndrome type 3
Other Names for this Disease
- Autoimmune polyendocrine syndrome type 3
- Polyglandular autoimmune syndrome type 3
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autoimmune condition that affects the body's endocrine glands. The syndrome, which typically affects women during middle age, results from failure of the glands to produce their hormones. This condition is characterized by autoimmune thyroiditis along with another organ-specific autoimmune disease. The other autoimmune diseases may include diabetes mellitus, pernicious anemia, vitiligo, alopecia, myasthenia gravis, and Sjogren's syndrome. The adrenal cortex (the outer layer of the adrenal gland) is not involved. There are three types of autoimmune polyglandular syndrome type 3:Autoimmune polyglandular syndrome (APS) type 3 is an
- APS3A - Autoimmune thyroiditis with immune-mediated diabetes mellitus (IMDM)
- APS3B - Autoimmune thyroiditis with pernicious anemia
- APS3C - Autoimmune thyroiditis with vitiligo and/or alopecia and/or other organ-specific autoimmune disease
Last updated: 1/15/2013
- Aung K. Type III Polyglandular Autoimmune Syndrome. Medscape Reference. January 2012; http://emedicine.medscape.com/article/124398-overview. Accessed 1/15/2013.
- Cihakova D. Polyglandular Autoimmune syndrome Type 3 (PAS 3) . Johns Hopkins Medical Institutions: Autoimmune Disease Research Center. September 2001; http://autoimmune.pathology.jhmi.edu/diseases.cfm?systemID=3&DiseaseID=68. Accessed 1/15/2013.
- Tariq SH. Polyglandular Deficiency Syndromes. The Merck Manual. November 2009; http://www.merckmanuals.com/professional/endocrine_and_metabolic_disorders/polyglandular_deficiency_syndromes/polyglandular_deficiency_syndromes.html. Accessed 1/15/2013.
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- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Autoimmune polyglandular syndrome type 3. Click on the link to view a sample search on this topic.