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Diseases

Genetic and Rare Diseases Information Center (GARD)

Left ventricular noncompaction


Other Names for this Disease
  • LVNC
  • Spongy myocardium
  • Left ventricular hypertrabeculation
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

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How might left ventricular noncompaction be treated?

There are no specific treatment guidelines for left ventricular noncompaction (LVNC). Medical management varies depending on clinical manifestations, left ventricular ejection fraction (LVEF), the presence or absence of arrhythmias, and the risk of thromboembolism.

Depending on the above factors, treatment might include: medications including diureticsACE inhibitors or Angiotensin II Receptor Blockers (ARBs), anticoagulants, and beta-blockers; an implantable cardioverter-defibrillator (ICD) or a pacemaker if an arrhythmia is present; and cardiac transplantation.[1][2][3]
Last updated: 5/26/2016

References
  1. Heidi M Connolly, Christine H Attenhofer-Jost. Isolated left ventricular noncompaction. UpToDate. April 2016; http://www.uptodate.com/contents/isolated-left-ventricular-noncompaction#H19.
  2. Treatment. CardiomyopathyUK. http://www.cardiomyopathy.org/left-ventricular-noncompaction/treatment-7. Accessed 5/26/2016.
  3. Bennett CE, Freudenberger R. The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy: Review of the Literature. Cardiology Research and Practice.. Jan 2016; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737020.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Left ventricular noncompaction. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • LVNC
  • Spongy myocardium
  • Left ventricular hypertrabeculation
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.