Linear and whorled nevoid hypermelanosis
Other Names for this Disease
- Linear and whorled hypermelanosis
- Nevoid hypermelanosis, linear and whorled
- Reticulate hyperpigmentation of Iijima
- Zebra-like hyperpigmentation
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There is very limited information regarding the treatment of linear and whorled nevoid hypermelanosis. Chemical peels and 2% hydroquinone for treatment of skin hyperpigmentation has been described. Due to the possible association with chromosome abnormalities and other symptoms, each person with linear and whorled nevoid hypermelanosis should undergo a thorough evaluation for developmental delays, growth retardation, and skeletal anomalies, such as facial and body asymmetry, and congenital heart defects.
Last updated: 3/18/2013
- Mehta V, Vasanth V, Balachandran C, Mathew M. Linear and whorled nevoid hypermelanosis. Int J Dermatol. 2011 Apr;50(4):491-2; http://www.ncbi.nlm.nih.gov/pubmed/21413967. Accessed 3/18/2013.
- Orphanet lists European clinical trials, research studies, and patient registries enrolling people with this condition.