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Diseases

Genetic and Rare Diseases Information Center (GARD)

Multifocal motor neuropathy


Other Names for this Disease
  • MMN
  • MMNCB
  • Multifocal motor neuropathy with conduction block
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Overview

Multifocal motor neuropathy (MMN) is a rare neuropathy characterized by progressive, asymmetric muscle weakness and atrophy (wasting).[1] Signs and symptoms include weakness in the hands and lower arms; cramping; involuntary contractions or twitching; and atrophy of affected muscles.[2] MMN is thought to be due to an abnormal immune response, but the underlying cause is not clear.[1] Most people treated with intravenous immune globulin (IVIG) have rapid improvement in weakness, but maintenance IVIG is usually required for sustained improvement.[1]
Last updated: 3/2/2016

References

  1. Dale Lange and Jessica Robinson-Papp. Multifocal motor neuropathy. UpToDate. Waltham, MA: UpToDate; January, 2015;
  2. NINDS Multifocal Motor Neuropathy Information Page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/multifocal_neuropathy/multifocal_neuropathy.htm. Accessed 5/1/2013.
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Basic Information

  • The GBS/CIDP Foundation International provides information about this condition. The GBS|CIDP Foundation International is a global non-profit organization supporting individuals and families affected by Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy (CIDP), and related syndromes through a commitment to support, education, research, and advocacy.
  • The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
  • The Neuropathy Action Foundation (NAF) provides an online brochure about Multifocal motor neuropathy. The NAF is dedicated to ensuring neuropathy patients obtain resources, information and tools to access individualized treatment to improve their quality of life.

In Depth Information

  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Multifocal motor neuropathy. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • MMN
  • MMNCB
  • Multifocal motor neuropathy with conduction block
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.