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Diseases

Genetic and Rare Diseases Information Center (GARD)

Renal nutcracker syndrome


Other Names for this Disease
  • Diffuse peritoneal leiomyomatosis
  • Disseminated peritoneal leiomyomatosis
  • DPL
  • Left renal vein entrapment syndrome
  • Leiomyomatosis peritonealis disseminate
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Overview

Renal nutcracker syndrome (NCS) is a condition that occurs when the left renal vein (the vein that carries blood purified by the left kidney) becomes compressed. The signs and symptoms of the condition can vary from person to person. Some affected people may be asymptomatic while others develop severe and persistent symptoms. When present, features of NCS may include blood in the urine (hematuria), orthostatic proteinuria, flank pain and/or abdominal pain. Some cases of mild NCS in children may be due to changes in body proportions associated with growth. Why NCS occurs or becomes symptomatic in adults is less clear. Treatment ranges from surveillance to surgical intervention and is based on the severity of symptoms and their expected reversibility when considering the affected person's age and stage of the syndrome.[1][2]
Last updated: 8/24/2015

References

  1. Gulleroglu K, Gulleroglu B, Baskin E. Nutcracker syndrome. World J Nephrol. November 2014; 3(4):277-281.
  2. Kurklinsky AK, Rooke TW. Nutcracker phenomenon and nutcracker syndrome. Mayo Clin Proc. June 2010; 85(6):552-559.
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In Depth Information

  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Renal nutcracker syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Diffuse peritoneal leiomyomatosis
  • Disseminated peritoneal leiomyomatosis
  • DPL
  • Left renal vein entrapment syndrome
  • Leiomyomatosis peritonealis disseminate
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.