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Diseases

Genetic and Rare Diseases Information Center (GARD)

Cerebral cavernous malformation


Other Names for this Disease
  • CCM
  • Cerebral cavernous hemangioma
  • Cavernous angioma
  • Cavernoma
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Treatment

Newline Maker

How might cerebral cavernous malformations be treated?

Seizures are usually treated with antiepileptic medications.[1][2] If seizures don't respond to medication, there is recurring bleeding in the brain, or the lesions are in a surgically accessible location, surgical removal of the lesion(s) using microsurgical techniques may be recommended.[1][3] Headaches are managed symptomatically and/or prophylactically. Other neurological symptoms may be managed through rehabilitation.[2]
Last updated: 12/15/2015

References
  1. NINDS Cerebral Cavernous Malformation Information Page. National Institute of Neurological Disorders and Stroke (NINDS). February 2015; http://www.ninds.nih.gov/disorders/cavernous_malformation/cavernous_malformation.htm. Accessed 12/14/2015.
  2. Morrison L, Akers A. Cerebral Cavernous Malformation, Familial. GeneReviews. May 2011; http://www.ncbi.nlm.nih.gov/books/NBK1293/. Accessed 12/14/2015.
  3. Altschul D. Intracranial Arteriovenous Malformation: Cavernous Angioma. Medscape Reference. April 2014; http://emedicine.medscape.com/article/252426-overview#a3. Accessed 12/15/2015.


Management Guidelines

  • GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions.

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Cerebral cavernous malformation. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
  • The Research Portfolio Online Reporting Tool (RePORT) provides access to reports, data, and analyses of research activities at the National Institutes of Health (NIH), including information on NIH expenditures and the results of NIH-supported research. Although these projects may not conduct studies on humans, you may want to contact the investigators to learn more. To search for studies, enter the disease name in the "Text Search" box. Then click "Submit Query".
Other Names for this Disease
  • CCM
  • Cerebral cavernous hemangioma
  • Cavernous angioma
  • Cavernoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.