Primary cutaneous amyloidosis
Other Names for this Disease
- Primary localized cutaneous amyloidosis
- Lichen amyloidosis familial
- Amyloidosis familial cutaneous lichen
- Amyloidosis 9
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amyloidosis, a group of conditions in which an abnormal protein (called amyloid) builds up in various organs and tissues throughout the body. In primary cutaneous amyloidosis, specifically, this protein accumulates in the skin. There are three main forms of primary cutaneous amyloidosis:Primary cutaneous amyloidosis is a form of
- Lichen amyloidosis - multiple itchy, raised spots which are scaly and red/brown in color. This rash generally affects the shins, thighs, feet and forearms.
- Macular amyloidosis - mild to severely itchy, flat, dusky-brown or greyish colored spots that may come together to form patches of darkened skin. This rash generally appears on the upper back between the shoulder blades, the chest and less commonly, the arms.
- Nodular amyloidosis - asymptomatic firm bumps that may be pinkish-brown to red in color. This rash may occur on the trunk, limbs, face, and/or genitals.
Last updated: 3/29/2016
- Amyloidosis. DermNet NZ. June 2014; http://www.dermnetnz.org/systemic/amyloidosis.html.
- Al Yahya RS. Treatment of primary cutaneous amyloidosis with laser: a review of the literature. Lasers Med Sci. March 2016; [Epub ahead of print]:
- AMYLOIDOSIS, PRIMARY LOCALIZED CUTANEOUS, 1. OMIM. May 2011; http://www.omim.org/entry/105250.
- AMYLOIDOSIS, PRIMARY LOCALIZED CUTANEOUS, 2. OMIM. May 2011; http://www.omim.org/entry/613955?search=cutaneous%20amyloidosis&highlight=cutaneous%20amyloidosi.
- Amyloidosis Awareness is an illustrated booklet for patients and physicians developed by Amyloidosis Support Groups Inc. Versions of the booklet are also available in Spanish and Portuguese.
- DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
Nodular Localized Cutaneous Amyloidosis
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
Primary localized cutaneous amyloidosis 1
Primary localized cutaneous amyloidosis 2
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Primary cutaneous amyloidosis. Click on the link to view a sample search on this topic.